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相关概念视频

Breathing01:05

Breathing

The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
Mechanism of Breathing I: Inspiration01:30

Mechanism of Breathing I: Inspiration

Introduction to Inspiration: The Respiratory System in Action
The respiratory system, an essential network for breathing, comprises the conducting and respiratory zones, each playing a crucial role in the overall process of respiration. Let us explore the detailed mechanism of inspiration, or inhalation, which is the first phase of the respiratory cycle.
Pathway of Air during Inspiration
During inspiration, air enters our body through the nose or mouth and moves through the conducting zone,...
Alterations in Respiration II01:30

Alterations in Respiration II

There are numerous types of normal and abnormal respiration. Based on ventilatory movements, breathing patterns are classified as regular, deep, or shallow. Examples include Biot's breathing, Cheyne-Stokes respiration, Kussmaul's breathing, hyperventilation, and hypoventilation. Each pattern is clinically significant and aids in evaluating patients.
In Biot's breathing, the respiratory rate and depth are irregular, alternating between periods of deep gasping and apnea. Common causes include...
Mechanism of Breathing II: Expiration01:23

Mechanism of Breathing II: Expiration

The Physiology of Expiration: A Seamless Respiratory Process
Expiration, or exhaling, is a complex physiological process that begins as the inspiratory muscles begin to relax. This relaxation triggers a series of events that epitomize the efficiency of the respiratory system.
Mechanism of Expiration:
Assessment of Ventilation II: Respiratory Depth and Rhythm01:29

Assessment of Ventilation II: Respiratory Depth and Rhythm

Respiratory Depth
Respiratory depth measures the volume of air inhaled or exhaled during a breath. It can vary from shallow to deep and typically remains consistent when a person is at rest or asleep. Occasionally, individuals will automatically inhale deeply, known as sighing, which inflates the lungs with more air than normal breathing.
To assess respiratory depth, observe the degree of chest excursion or movement:
Respiratory Volumes01:15

Respiratory Volumes

Respiratory volumes are crucial metrics, meticulously measured to quantify the air exchanged in and out of the lungs during various phases of the breathing cycle. These precise measurements are vital for assessing lung function, diagnosing respiratory conditions, and monitoring overall respiratory health. Each parameter provides specific insights into the mechanics of breathing and the functional capacity of the lungs.
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...

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相关实验视频

Updated: Jun 20, 2026

A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways
09:39

A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways

Published on: May 9, 2016

"呼吸"的囊泡可以呼吸.

Shaoyong Yu1, Tony Azzam, Isabelle Rouiller

  • 1Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec, H3A 2K6, Canada.

Journal of the American Chemical Society
|September 3, 2009
PubMed
概括
此摘要是机器生成的。

这项研究引入了具有独特"呼吸"能力的pH反应性囊泡,可逆地改变大小并允许物种扩散. 这些智能囊泡提供了快速的质子传输和受控的透性.

更多相关视频

Breath Collection from Children for Disease Biomarker Discovery
06:09

Breath Collection from Children for Disease Biomarker Discovery

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Method to Obtain Pattern of Breathing in Senescent Mice through Unrestrained Barometric Plethysmography
09:13

Method to Obtain Pattern of Breathing in Senescent Mice through Unrestrained Barometric Plethysmography

Published on: April 28, 2020

相关实验视频

Last Updated: Jun 20, 2026

A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways
09:39

A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways

Published on: May 9, 2016

Breath Collection from Children for Disease Biomarker Discovery
06:09

Breath Collection from Children for Disease Biomarker Discovery

Published on: February 14, 2019

Method to Obtain Pattern of Breathing in Senescent Mice through Unrestrained Barometric Plethysmography
09:13

Method to Obtain Pattern of Breathing in Senescent Mice through Unrestrained Barometric Plethysmography

Published on: April 28, 2020

科学领域:

  • 材料科学 材料科学 材料科学
  • 聚合物化学 聚合物化学
  • 纳米技术纳米技术

背景情况:

  • 囊泡在药物输送和纳米技术中至关重要.
  • 响应pH的材料提供了对囊泡属性的动态控制.
  • 控制胀和透性是先进应用的关键.

研究的目的:

  • 为了合成和表征一种用于pH响应囊泡的新型triblock共聚物.
  • 为了研究这些囊泡的pH诱导的结构变化和体积转换.
  • 为了评估pH值变化对囊泡透性和离子传输的影响.

主要方法:

  • 通过ATRP合成聚乙烯氧化物-块-聚乙烯-块-聚二甲基酸 (PEO-b-PS-b-PDEA).
  • 囊泡在高pH值下自组装 (大约 10.4.4) 的情况.
  • 低温传导电子显微镜 (cryo-TEM) 用于结构分析.
  • 囊泡大小,壁厚度和透性的pH依赖性表征.

主要成果:

  • 囊泡表现出三层壁结构 (PS-PDEA-PS) 具有pH依赖的胀.
  • 一个显著的,可逆的体积变化 (大约. 7倍) 发生在由于PDEA质子和水合而导致的pH值下降时.
  • 降低pH值会导致囊泡大小增加,壁厚增加,PS层发生裂,增强水和质子的透性.
  • 快速放松时间 (大约2小时) 1分钟) 和在pH值10.4到3.4.4之间观察到的高可逆性.

结论:

  • 合成的PEO-b-PS-b-PDEA共聚合物形成了强大的pH响应囊泡,具有可调节的特性.
  • "呼吸"机制允许物种的控制扩散和快速的质子传输.
  • 这些囊泡有可能用于需要动态体积变化和受控透性的应用,例如智能药物输送系统.