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通过DOCK交换因子激活Rho GTPases是由一个核酸传感器介导的

Jing Yang1, Ziguo Zhang, S Mark Roe

  • 1Section of Structural Biology, Institute of Cancer Research, Chester Beatty Laboratories, 237 Fulham Road, London SW3 6JB, UK.

Science (New York, N.Y.)
|September 12, 2009
PubMed
概括

DOCK9-Cdc42复合体揭示了一种用于Rho GTPase激活的新型核酸传感器机制. 这种传感器促进了瓜二酸盐的释放和瓜三酸盐的排出,澄清了瓜核酸交换因子的催化循环.

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