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矿工暴露于粉的影响

S L Rifat¹, M R Eastwood, D R McLachlan

¹Department of Psychiatry, University of Toronto, Canada.

Lancet (London, England)

|November 10, 1990

概括

接触麦金泰尔粉末 () 的矿工没有增加神经诊断,但在认知测试中表现更差. 增加的暴露时间与较差的认知评分相关,这表明的潜在神经毒性.

科学领域:

职业健康职业健康职业健康
神经科学是一个神经科学.
毒理学毒理学毒理学

背景情况:

麦金泰尔粉,含有和氧化,从1944年至1979年在安大略省的矿山中使用.
它被用作预防性预防性肺病的预防措施.

研究的目的:

在矿工中调查麦金泰尔粉暴露的潜在神经毒性影响.
评估暴露与神经健康结果之间的关系.

主要方法:

在1988年至1989年期间进行了一项疾病患病率研究.
暴露和非暴露矿工之间神经障碍诊断和认知状态检查的比较.

主要成果:

在报告的神经疾病诊断中没有显著差异.
暴露的矿工在认知状态检查中表现较差.
较高比例的暴露矿工在受损认知范围中得分.
认知障碍的可能性随着暴露的持续时间而增加.

结论:

这些发现表明,与McIntyre粉末的慢性暴露相关的潜在神经毒性.
职业暴露可能会对认知功能产生不利影响.
对的神经影响的进一步研究是有必要的.

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