Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Current Trends in Nursing I01:28

Current Trends in Nursing I

Current trends in nursing include:
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
Aging01:26

Aging

Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Correction: Physical activity and cohabitation status moderate the link between diabetes mellitus and cognitive performance in a community-dwelling elderly population in Germany.

PloS one·2026
Same author

Modification of Hospitalization Risk by Gender and Dementia Status Between the Ages of 85 and 95 in a German Cohort Based on Health Claims Data.

BMC health services research·2026
Same author

Forecast of dementia prevalence in Germany and subnational regions until 2060 using microsimulation.

European journal of epidemiology·2026
Same author

Examining morbidity and mortality trajectory profiles of hypertension, diabetes and dementia across healthcare systems: an analysis of Catalan and German administrative medical data for the years 2010 to 2019.

Population health metrics·2026
Same author

Individual and combined associations of physical activity and cognitive function with all-cause mortality in older men and women: a prospective analysis of the German National Cohort (NAKO).

BMC geriatrics·2026
Same author

Ageing populations: new challenges in longevity.

BMC public health·2025

相关实验视频

人口老龄化:未来的挑战

Kaare Christensen1, Gabriele Doblhammer, Roland Rau

  • 1Danish Ageing Research Centre, University of Southern Denmark, Odense, Denmark. kchristensen@health.sdu.dk

Lancet (London, England)
|October 6, 2009
PubMed
概括

大多数在发达国家出生的婴儿可能活到100岁,老龄化人口可能在没有残疾的情况下活得更长. 研究表明,衰老是可以修改的,为未来的社会挑战提供了希望.

科学领域:

  • 人口统计学 人口统计学
  • 老年学是指老年学的学科.
  • 公共卫生 公共卫生

背景情况:

  • 全球预期寿命在过去的两个世纪里显著增加.
  • 发达国家面临着人口老龄化,原因是生育率低,寿命长.
  • 一个关键的问题是,延长寿命是否与延长健康寿命相关.

研究的目的:

  • 探索持续增长的预期寿命所带来的影响.
  • 研究长寿与功能限制之间的关系.
  • 评估可修改的衰老过程对影响人口老龄化的潜力.

主要方法:

  • 对发达国家人口趋势的分析.
  • 审查关于衰老过程和功能限制的研究.
  • 预测未来的预期寿命和健康情况.

主要成果:

  • 预期寿命的持续增长表明,2000年以后出生的许多人可能达到100岁.
  • 发达国家的人口老龄化是由于人口结构的变化.
  • 新兴的研究表明,衰老过程是可以修改的,有可能延长无残疾的寿命.

结论:

相关实验视频

  • 长寿正在增加,但同时推迟残疾仍然是一个开放的问题.
  • 可修改的老龄化过程,医学进步和社会适应对于应对老龄化人口的挑战至关重要.
  • 未来的社会结构必须适应,以支持更长,更健康的寿命.