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Updated: Jun 19, 2026

Combining Wet and Dry Lab Techniques to Guide the Crystallization of Large Coiled-coil Containing Proteins
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Published on: January 6, 2017

对于分裂蛋白质蛋白酶传感器的一种自抑制的卷绕卷绕设计策略

Sujan S Shekhawat1, Jason R Porter, Akshay Sriprasad

  • 1Department of Chemistry & Biochemistry, University of Arizona, Tucson, Arizona 85721, USA.

Journal of the American Chemical Society
|October 7, 2009
PubMed
概括

研究人员开发了新的遗传编码生物传感器,这些生物传感器在蛋白酶活动时被激活. 这种新的自抑制设计为检测像caspase-3这样的蛋白酶提供了1000倍的信号增强.

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The Importance of Correct Protein Concentration for Kinetics and Affinity Determination in Structure-function Analysis19:16

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