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Updated: Jun 19, 2026

Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation
08:48

Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation

Published on: January 26, 2016

阿扎-β3-cyclopeptides:一种新的控制化的方法

Clémence Mocquet1, Arnaud Salaün, Paul Claudon

  • 1ICMV and CSM, UMR CNRS 6226, Université de Rennes I, 35042 Rennes Cedex, France.

Journal of the American Chemical Society
|October 8, 2009
PubMed
概括

研究人员使用水或氨基酸合成了新的宏循环. 这些稳定的结构展示了动态的选,首次控制了较大的分子中的性.

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Chirality in Nature

Chirality is the most intriguing yet essential facet of nature, governing life’s biochemical processes and precision. It can be observed from a snail shell pattern in a macroscopic world to an amino acid, the minutest building block of life. Most of the snails around the world have right-coiled shells because of the intrinsic chirality in their genes. All the amino acids present in the human body exist in an enantiomerically pure state, except for glycine - the sole achiral amino acid. The...
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In the presence of an aqueous base and a halogen, primary amides can lose the carbonyl (as carbon dioxide) and undergo rearrangement to form primary amines. This reaction, called the Hofmann rearrangement, can produce primary amines (aryl and alkyl) in high yields without contamination by secondary and tertiary amines.
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