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Updated: Jun 19, 2026

A Two-Step Strategy that Combines Epigenetic Modification and Biomechanical Cues to Generate Mammalian Pluripotent Cells
08:01

A Two-Step Strategy that Combines Epigenetic Modification and Biomechanical Cues to Generate Mammalian Pluripotent Cells

Published on: August 29, 2020

植入后表皮质细胞的表观遗传逆转为多能胚胎干细胞

Siqin Bao1, Fuchou Tang1, Xihe Li2

  • 1Wellcome Trust/Cancer Research UK Gurdon Institute of Cancer and Developmental Biology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QN, UK.

Nature
|October 10, 2009
PubMed
概括

研究人员通过克服表观遗传障碍,将先进的表皮质细胞重新编程成胚胎干细胞样细胞 (rESCs). 这些重新编程的细胞可以为嵌合体中的组织和生殖细胞做出贡献,这表明多能性重新获得的潜力.

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