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Updated: Nov 7, 2025

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

Published on: August 16, 2018

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gabapentin受体α2delta-1 是一个神经元中的血栓蛋白受体,负责激发性中枢神经系统协同生成

Cagla Eroglu1, Nicola J Allen, Michael W Susman

  • 1Duke University Medical Center, Cell Biology Department, Durham, NC 27710, USA. c.eroglu@cellbio.duke.edu

Cell
|October 13, 2009
PubMed
概括

研究人员确定alpha2delta-1是血栓松丁的关键受体,这是促进中枢神经系统 (CNS) 突触形成的蛋白质. 药物 gabapentin 阻断了这种相互作用,抑制了新的突触发育.

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Quantifying Synapses: an Immunocytochemistry-based Assay to Quantify Synapse Number18:11

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