转子子诱导的表观遗传变化导致了瓜子的性别确定
Antoine Martin1, Christelle Troadec, Adnane Boualem
1INRA-CNRS, UMR1165, Unité de Recherche en Génomique Végétale, 2 rue Gaston Crémieux, F-91057 Evry, France.
Nature
|October 23, 2009
概括
植物的性别决定涉及瓜子的表观遗传变化,其中转子体插入会改变CmWIP1基因表达. 这控制了雄性,雌性和雌性花的发展,促进了物种进化的遗传多样性.
科学领域:
- 植物遗传学 植物遗传学
- 表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.
- 发育生物学是发展生物学.
背景情况:
- 植物的性别决定涉及从双性恋的花中发展单性花,促进交叉和遗传变异性.
- 在西瓜 (Cucumis melo) 中,性形式由andromonoecious (a) 和gynoecious (g) 位点的等位体调节.
- 安德罗莫诺基因 (CmACS-7) 编码一种乙烯生物合成酶,抑制雌花的茎发育.
研究的目的:
- 为了研究基因性瓜子系中从雄性花向雌性花的转变背后的分子机制.
- 阐明表观遗传修饰在调节花发育和西瓜的性别决定中的作用.
主要方法:
- 在CmWIP1基因的促进体内表观遗传变化的分析.
- 对转子子插入和DNA甲基化模式的研究.
- 对CmWIP1和CmACS-7的基因表达分析.
- 功能性研究以确定CmWIP1在花发育中的作用.
主要成果:
- 转变为雌性花在中是由CmWIP1促进体的表观遗传变化引发的.
- 转子体插入启动并维持DNA甲基化扩散到CmWIP1促进体.
- CmWIP1的表达导致了带流产,从而产生单性雄性花.
- CmWIP1间接抑制CmACS-7的表达,从而使茎发育成为可能.
结论:
- 提出了一个模型,其中CmACS-7和CmWIP1相互作用,以控制西瓜中雄性,雌性和雌性花的发展.
- 通过转子子诱导的DNA甲基化进行表观遗传调节,在植物的性别决定中起着至关重要的作用.
- 了解这些机制可以有助于改善作物产量和特征的育种计划.
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