在低水平酒精消费者中,高密度脂蛋白胆固醇的性别差异
G Weidner1, S L Connor, M A Chesney
1Department of Psychology, State University of New York, Stony Brook 11794.
Circulation
|January 1, 1991
概括
适度饮酒,即使是每天一杯,与女性高密度脂蛋白胆固醇 (HDL-C) 的增加有关,但男性并非如此. 这表明女性可能会在摄入量低于男性的酒精中体验到HDL-C的好处.
科学领域:
- 心血管健康 心血管健康
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 高密度脂蛋白胆固醇 (HDL-C) 是心血管健康的关键指标.
- 了解低水平的酒精消费与HDL-C之间的关系对于公共卫生指南很重要.
研究的目的:
- 为了研究低酒精消费 (≤1饮料/天) 和高密度脂蛋白胆固醇 (HDL-C) 水平在社区居住的男性和女性之间的关联.
- 为了确定低酒精摄入量与HDL-C之间的关系中是否存在性别差异.
主要方法:
- 纵向研究设计,数据采集在两个时间点,隔12个月.
- 利用自我报告的酒精消耗和血脂和脂蛋白水平的临床评估.
- 分析了来自社区生活的男性和女性样本的数据,控制了酒精摄入量.
主要成果:
- 在男性中,每天≤1杯酒的酒精消费与HDL-C水平没有显著的关联.
- 在女性中,每天≤1饮料的酒精消费与更高的HDL-C水平有关.
- 在女性中,酒精摄入量与HDL-C之间的积极关联甚至在低消费水平下也被观察到.
结论:
- 这些发现表明,酒精对高密度胆固醇水平的有益影响可能发生在女性相比男性的低消费门.
- 低水平的酒精消费可能会根据性别对HDL-C产生不同的影响.
- 需要进一步的研究来阐明酒精和HDL-C之间性别特异性关联背后的机制.
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