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Updated: Jun 10, 2026

Analyzing and Building Nucleic Acid Structures with 3DNA
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Published on: April 26, 2013

DNA形状在蛋白质-DNA识别中的作用

Remo Rohs1, Sean M West, Alona Sosinsky

  • 1Howard Hughes Medical Institute, Center for Computational Biology and Bioinformatics, Department of Biochemistry and Molecular Biophysics, Columbia University, 1130 Saint Nicholas Avenue, New York, New York 10032, USA.

Nature
|October 30, 2009
PubMed
概括

蛋白质通过感知它的形状和电性质来识别DNA,特别是在小槽中. 这项研究表明,氨酸残留物与狭窄的DNA小沟结合是DNA识别的关键机制.

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