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Updated: Jun 19, 2026

Preparation of N-(2-alkoxyvinyl)sulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines
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评估用于合成laulimalide的过渡金属催化转化

Barry M Trost1, Dominique Amans, W Michael Seganish

  • 1Department of Chemistry, Stanford University, Stanford, California 94305-5080, USA. bmtrost@stanford.edu

Journal of the American Chemical Society
|November 7, 2009
PubMed
概括

研究人员合成了laulimalide,这是一种具有微管稳定活性的海洋宏化物. 这种高效的合成途径还产生了一种强大的细胞毒性类似物,为药物发现提供了新的途径.

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