相关实验视频
Updated: Jun 18, 2026

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Quantifying Abdominal Pigmentation in Drosophila melanogaster
Published on: June 1, 2017
在物种内部的多态化到物种间的分歧:Drosophila的色素遗传学
Patricia J Wittkopp1, Emma E Stewart, Lisa L Arnold
1Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI 48109, USA. wittkopp@umich.edu
概括
棕色和色基因的遗传变化影响果颜色差异. 在物种化之前的等位基因对物种内部的变异和物种间的分歧都有贡献.
科学领域:
- 进化遗传学的进化遗传学
- 人口遗传学 人口遗传学
- 分子进化的分子进化.
背景情况:
- 了解表型差异的遗传基础对于进化研究至关重要.
- 在物种内部的遗传变异和物种间的差异之间的关系还不太清楚.
研究的目的:
- 为了研究色素变异的基因基础在多虫物种的色素分歧.
- 探索常态遗传变异在推动物种内部多态和物种间分歧中的作用.
主要方法:
- 对Drosophila物种进行比较基因组学分析.
- 研究色和黑色基因中的遗传变化.
- 评估特定基因对表型变异的贡献.
主要成果:
- 色基因的非编码变化和色基因的相关变化有助于Drosophila物种之间的色素分歧.
- 在某种物种中固定的与棕色和木相关的等位基因也会导致其他物种内的遗传变异.
- 多种遗传配置可以导致种群内类似的色素表型.
结论:
- 影响色素差异的遗传变异早于物种化事件.
- 祖先种群中持续存在的遗传变异是内部多态和跨物种分歧的关键来源.
- 这凸显了祖先变异在塑造进化轨迹中的重要性.
相关概念视频
Position-effect Variegation
In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.
Epistasis
In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...
Background and Environment Affect Phenotype
Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...

