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Updated: Jun 18, 2026

Enzymatic Synthesis of Epoxidized Metabolites of Docosahexaenoic, Eicosapentaenoic, and Arachidonic Acids
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Enzymatic Synthesis of Epoxidized Metabolites of Docosahexaenoic, Eicosapentaenoic, and Arachidonic Acids

Published on: June 28, 2019

IspG将一个环氧基质类似物转化为 (E) -4-基-3-甲基-2-乙烯二酸盐:对IspG催化在异oprenoid生物合成中的含义

Rodney L Nyland1, Youli Xiao, Pinghua Liu

  • 1Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

Journal of the American Chemical Society
|November 19, 2009
PubMed
概括

研究人员为酶IspG.合成了一个拟议的中间体, (2R,3R) -4-基-3-甲基-2,3-epoxybutanyl二酸盐 (Epoxy-HMBPP),用于酶IspG. 这项研究证实了Epoxy-HMBPP是一种基质,进步了对异oprenoid生物合成的理解.

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