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Updated: Aug 8, 2026

Visualization of Caenorhabditis elegans Cuticular Structures Using the Lipophilic Vital Dye DiI
08:22

Visualization of Caenorhabditis elegans Cuticular Structures Using the Lipophilic Vital Dye DiI

Published on: January 30, 2012

由C. elegans的底层膜原体突变引起的胚胎致死性

X D Guo1, J J Johnson, J M Kramer

  • 1Department of Biological Sciences, University of Illinois, Chicago 60680.

Nature
|February 21, 1991
PubMed
概括

对于发育至关重要的底层膜的缺陷会导致胚胎死亡. 这项研究确定了C. elegans中的α 1(IV) 原基因 (emb-9) 中的突变,将底层膜完整性与胚胎发育联系起来.

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Measuring Embryonic Viability and Brood Size in Caenorhabditis elegans06:24

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Lethal Alleles02:41

Lethal Alleles

Agouti: A Lethal Allele
Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...