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Understanding the Development of Compensatory Pathways in a Mutant Malaria Parasite Harbouring Hypomorphic Allele of Plant-Like Kinases
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积极选择的G6PD-Mahidol突变降低了东南亚人中的Plasmodium vivax密度

Chalisa Louicharoen1, Etienne Patin, Richard Paul

  • 1Institut Pasteur, Laboratoire de la Génétique de la réponse aux infections chez l'homme, 75724 Paris, France.

Science (New York, N.Y.)
|December 17, 2009
PubMed
概括

葡萄糖-6-酸脱酶 (G6PD) 缺乏提供了对疟疾的保护. G6PD-Mahidol变种特别降低了Plasmodium vivax寄生虫密度,这表明这种疟疾类型推动了它的选择.

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