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Updated: Apr 11, 2026

Assaying the Ability of Diffusible Signaling Molecules to Reorient Embryonic Spinal Commissural Axons
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分泌的塞马福林控制脊柱分布和在产后中枢神经系统的形态发生

Tracy S Tran1, Maria E Rubio, Roger L Clem

  • 1Solomon H. Snyder Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

Nature
|December 17, 2009
PubMed
概括

分泌的semaphorin Sema3F负面调节了中枢神经系统 (CNS) 中的树突脊髓发育和突触结构. 失去Sema3F信号增加了脊柱数量和大小,影响了突触功能和中枢神经系统连接.

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