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Updated: Jun 17, 2026

A Reporter Assay to Analyze Intronic microRNA Maturation in Mammalian Cells
06:48

A Reporter Assay to Analyze Intronic microRNA Maturation in Mammalian Cells

Published on: June 16, 2022

由c-Myc控制的HnRNP蛋白质去调节酸激酶mRNA在癌症中的拼接

Charles J David1, Mo Chen, Marcela Assanah

  • 1Department of Biological Sciences, Columbia University, New York, New York 10027, USA.

Nature
|December 17, 2009
PubMed
概括

癌症细胞利用有氧糖解来增长,通过表达胚胎的酸盐激酶异型 (PKM2). 这项研究确定了hnRNP和c-Myc作为PKM2剪接的关键调节者,这对瘤增殖至关重要.

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