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一个小细胞肺癌基因组具有复杂的烟草暴露的签名

Erin D Pleasance1, Philip J Stephens, Sarah O'Meara

  • 1Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.

Nature
|December 18, 2009
PubMed
概括

烟草吸烟会通过突变DNA引起癌症. 这项研究对肺癌细胞系进行了测序,揭示了成千上万的突变,并确定了基因重排,为癌症发展提供了洞察力.

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