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Updated: Jun 17, 2026

Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1
08:53

Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1

Published on: February 17, 2011

这种SUMO修饰途径与BRCA1对基因毒性压力反应有关

Joanna R Morris1, Chris Boutell, Melanie Keppler

  • 1Department of Medical and Molecular Genetics, King's College London, Guy's Medical School Campus, London SE1 9RT, UK. jo.morris@genetics.kcl.ac.uk

Nature
|December 18, 2009
PubMed
概括

该SUMOylation途径调节BRCA1,这是DNA损伤修复中的关键蛋白质. 这种修改增强了BRCA1的功能.

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Functional Assessment of BRCA1 variants using CRISPR-Mediated Base Editors09:22

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Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy08:31

Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy

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