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Updated: Jun 17, 2026

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes
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溶剂对大肠杆菌二酸盐减少酶的催化作用

E Joel Loveridge1, Lai-Hock Tey, Rudolf K Allemann

  • 1School of Chemistry, Cardiff University, Main Building, Park Place, Cardiff CF10 3AT, UK.

Journal of the American Chemical Society
|January 6, 2010
PubMed
概括

反应介质的介电常数,而不是粘度,会影响由二叶酸减少酶 (DHFR) 催化化物转移的速率. 溶剂的变化没有影响动态同位素效应或其温度依赖.

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