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Updated: Jun 17, 2026

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
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在ES细胞中,JARID2调节了多镇压复合体2与ES细胞的基因的结合

Diego Pasini1, Paul A C Cloos, Julian Walfridsson

  • 1Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Ole Maaløes Vej 5, 2200 Copenhagen N, Denmark.

Nature
|January 16, 2010
PubMed
概括

含有Jumonji和ARID域的蛋白质JARID2对于招募聚合组 (PcG) 蛋白来向基因至关重要. 这种招募对于基因抑制,干细胞分化和正常发育至关重要.

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