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Updated: May 8, 2026

Reprogramming Human Somatic Cells into Induced Pluripotent Stem Cells (iPSCs) Using Retroviral Vector with GFP
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Published on: April 3, 2012

KAP1控制胚胎干细胞中的内源逆转录病毒

Helen M Rowe1, Johan Jakobsson, Daniel Mesnard

  • 1School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.

Nature
|January 16, 2010
PubMed
概括

与KRAB相关的蛋白1 (KAP1) 在早期发育中控制内源逆转录病毒 (ERV). 在小鼠胚胎干细胞和胚胎中KAP1的删除导致了显著的ERV上调,突出了它在基因组完整性中的作用.

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