青少年和成年人的胎儿酒精综合征
A P Streissguth1, J M Aase, S K Clarren
1Department of Psychiatry, Child Development/Mental Retardation Center, Seattle, WA.
JAMA
|April 17, 1991
概括
胎儿酒精综合征 (FAS) 呈现出明显的面部形和发育问题. 长期来看,患有FAS的个体会经历认知缺陷和适应不良的行为,这给成年人带来了重大的管理挑战.
科学领域:
- 神经科学是一个神经科学.
- 发育儿科 发育儿科
- 公共卫生 公共卫生
背景情况:
- 胎儿酒精综合征 (FAS) 是可预防的出生缺陷的主要原因.
- 怀孕期间接触酒精会导致一系列神经发育障碍.
- 了解FAS的长期表现对于有效管理至关重要.
研究的目的:
- 描述青少年和成年人胎儿酒精产的表现.
- 描述患有FAS的个体在童年以后的身体,认知和行为结果.
- 突出在成人群体中管理FAS的挑战.
主要方法:
- 对61名被诊断患有胎儿酒精综合征或其影响的青少年和成人临床数据的回顾性分析.
- 评估身体特征,认知功能 (IQ),学业成绩和行为模式.
- 家庭环境稳定性的评估.
主要成果:
- 在患有FAS的个体中,青春期后面部特征变得不那么明显.
- 一致的发现包括矮身和小头症,体重更接近平均值.
- 平均智商为68,差异很大;学术表现平均为二年级至四年级水平,特别是算术缺陷.
- 不适应性行为 (判断力差,易分心,社交暗示困难) 和不稳定的家庭环境普遍存在.
结论:
- 胎儿酒精综合征是一种终身的疾病,可预测到成年后的进展.
- 适应不良行为是FAS成年人的首要管理挑战.
- 早期干预和持续的支持对FAS患者一生至关重要.
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