MicroTUB(B3) 细胞和大脑的发育
1Howard Hughes Medical Institute, Cambridge, MA 02139, USA.
Cell
|January 21, 2010
概括
TUBB3基因的突变通过影响微管体动力学来破坏神经元发育. 这会影响神经元迁移,并导致各种神经疾病症状.
科学领域:
- 神经科学是一个神经科学.
- 细胞生物学 细胞生物学
- 遗传学 是一个遗传学.
背景情况:
- 微管网络对于神经元的发育和功能至关重要.
- 已知氨酸编码基因的突变会损害神经元迁移.
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