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精神压力对心室功能在心脏病发作后患者的影响. 一个侵入性的血液动力学调查
G Mazzuero1, P L Temporelli, L Tavazzi
1Division of Cardiology, Medical Rehabilitation Center, Veruno, Italy.
Circulation
|April 1, 1991
概括
在心脏病发作后的患者中,精神压力显著影响心脏功能,导致中风体积减少和肺压力增加. 这些影响与心率和血压变化无关,并且长期存在.
科学领域:
- 心脏病学 心脏病学
- 心理生理学 心理生理学
背景情况:
- 冠状动脉疾病患者容易受到心血管压力.
- 心理压力可以引发不良的心脏事件.
研究的目的:
- 评估精神压力对心室功能在心肌梗塞后患者的影响.
- 通过非侵入性参数或运动测试来确定心理压力诱导的血液动力学变化是否可预测.
主要方法:
- 88名心脏病发作后患者在天-甘兹导管治疗期间接受了心理算术任务.
- 监测血液动力学参数,包括心率,血压,肺压和中风体积.
- 一小部分患者也接受了运动测试,并在一年后重复评估.
主要成果:
- 脑力算术导致心率,血压和肺压的显著增加 (p < 0.001).
- 在精神压力期间,中风的平均体积显著下降 (p < 0.001).
- 血液动力学变化无法通过非侵入性措施或运动测试来预测,并且在心脏病发作后的一年内保持稳定.
结论:
- 精神压力可以诱导冠心病患者中中心血液动力学显著恶化.
- 这些由压力引起的变化独立于心率和血压变化以及运动反应.
- 由于精神压力的心血管激活是持续和稳定的,随着时间的推移.
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