相关实验视频

Updated: Jun 16, 2026

Purification of Ubiquitinated p53 Proteins from Mammalian Cells
10:55

Purification of Ubiquitinated p53 Proteins from Mammalian Cells

Published on: March 21, 2022

USP10通过对p53进行脱化来调节p53的局部化和稳定性

Jian Yuan1, Kuntian Luo, Lizhi Zhang

  • 1Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.

Cell
|January 26, 2010
PubMed
概括

USP10二基酸 p53,逆转Mdm2诱导的降解和核出口. 这种细胞质蛋白酶在DNA损伤后稳定p53,抑制瘤生长,并为野生类型的p53癌症提供了一个新的目标.

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Detection of Protein Ubiquitination

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Comparative Strategies for Ubiquitination Detection in Mammalian Cell Lysates Using SMAD2/SMURF2 as a Model09:00

Comparative Strategies for Ubiquitination Detection in Mammalian Cell Lysates Using SMAD2/SMURF2 as a Model

Published on: April 17, 2026

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