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细胞蛋白的N端乙化产生特定的降解信号

Cheol-Sang Hwang1, Anna Shemorry, Alexander Varshavsky

  • 1Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA.

Science (New York, N.Y.)
|January 30, 2010
PubMed
概括

蛋白质的N端乙化,在真核生物中很常见,可以为降解发出信号. 这项研究确定了乙化N-终端残留物作为酵母中的Doa10泛素酶识别的关键降解信号 (AcN-降解子).

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