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Updated: Jun 16, 2026

Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy
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通过固态核磁共振光谱检测的Y145Stop人类蛋白粉样纤维的形状灵活性

Jonathan J Helmus1, Krystyna Surewicz, Witold K Surewicz

  • 1Department of Chemistry, The Ohio State University, Columbus, Ohio 43210, USA.

Journal of the American Chemical Society
|February 4, 2010
PubMed
概括

人类蛋白 (huPrP23-144) amyloid 的 N-终端域是灵活的,并且类似于随机卷轴. 核心残留物表现出限制运动,但粉样核中的一些缓慢动态表明潜在的化学交换现象.

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