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Updated: May 23, 2026

Assessment of DNA Contamination in RNA Samples Based on Ribosomal DNA
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Assessment of DNA Contamination in RNA Samples Based on Ribosomal DNA

Published on: January 22, 2018

丰富的核糖体RNA基因拷贝维持了基因组的完整性

Satoru Ide1, Takaaki Miyazaki, Hisaji Maki

  • 1National Institute of Genetics, Sokendai, 1111 Yata, Mishima, 411-8540 Japan.

Science (New York, N.Y.)
|February 6, 2010
PubMed
概括

在酵母中失去额外的核糖体RNA基因重复 (rDNA) 会增加对DNA损伤的敏感性. 这是因为活跃的rDNA转录会破坏姐妹染色体的凝聚力,损害DNA修复. 额外的rDNA副本通过促进凝聚力和修复来保护细胞.

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Single Nucleotide Polymorphism-sensitive FISH Detection of Locus-specific Ribosomal RNA Transcription in Drosophila melanogaster04:59

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