在高血压吸烟者中,循环系统血压的升高. 一个病例控制研究研究
S J Mann1, G D James, R S Wang
1Cardiovascular and Hypertension Center, New York Hospital-Cornell Medical Center, NY 10021.
JAMA
|May 1, 1991
概括
患有高血压的吸烟者有类似的办公室血压读数,但比非吸烟者,尤其是50岁以上的非吸烟者,白天的门诊系统血压更高. 这突显了吸烟高血压患者血压测量的悖论.
科学领域:
- 心脏病学 心脏病学
- 高血压研究 高血压研究
- 公共卫生 公共卫生
背景情况:
- 众所周知,吸烟会提高血压.
- 与非吸烟者相比,吸烟者的办公室血压测量通常不反映这种升高.
- 传统的血压读数与吸烟者的实际心血管应变之间存在差异.
研究的目的:
- 调查吸烟者和非吸烟者的类似办公室血压的悖论.
- 为了比较高血压吸烟者和非吸烟者的24小时门诊血压监测 (ABPM).
- 为了识别吸烟者和非吸烟者之间血压模式的年龄相关差异.
主要方法:
- 一项涉及59名未经治疗的高血压吸烟者和118名匹配的非吸烟高血压患者的比较研究.
- 测量办公室血压和24小时门诊血压.
- 分析醒觉和睡眠血压读数,按年龄分层 (50岁以下和50岁以上).
主要成果:
- 办公室血压在吸烟者 (141/93毫米升) 和非吸烟者 (142/93毫米升) 之间是可比的.
- 醒来时,抽烟者 (145毫米升) 与非吸烟者 (140毫米升) 的循环静脉血压显著更高.
- 这种差异在50岁以上的个体 (153 mmHg对142 mmHg) 中是明显的,但在50岁以下的人中并非如此.
结论:
- 50岁以上患有高血压的吸烟者,比不吸烟者有更高的白天通行系统血压.
- 办公室血压测量可能低估了老年高血压患者吸烟对心血管的影响.
- 门诊血压监测对于准确评估高血压吸烟者的血压至关重要,特别是老年人群.
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