带用于破碎的染色体
1Cell Cycle & Cancer Biology, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA. gjg@omrf.org
Cell
|February 10, 2010
概括
在细胞分裂过程中,染色质结合物防止缺少中间体的染色体片段在果神经细胞中引起灾难性的错误. 这一发现突显了一种新的机制,用于在线粒分裂过程中保持基因组稳定性.
科学领域:
- 细胞生物学 细胞生物学
- 遗传学 是一个遗传学.
- 分子生物学分子生物学
背景情况:
- 分解是一种关键的细胞分裂过程,对生长和修复至关重要.
- 分离过程中DNA双链断裂对基因组完整性构成重大威胁.
- 没有中间体的染色体碎片不能正确分离,导致形积分.
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