相关实验视频
左侧传染性内心炎的年龄依赖性概况:一个3中心经验
Javier López1, Ana Revilla, Isidre Vilacosta
1Instituto de Ciencias del Corazón, Hospital Clínico Universitario, Valladolid, Spain. javihouston@yahoo.es
Circulation
|February 10, 2010
概括
年龄显著影响传染性内心炎,老年患者的膜损伤较少,但手术死亡率较高. 这项研究分析了600例病例,以了解这种严重的心脏感染中与年龄相关的差异.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 年龄对传染性内心炎 (IE) 特征的影响尚不清楚.
- 这项研究提供了迄今为止最大的系列,分析左侧IE的特定年龄特征.
- 为了进行全面的分析,患者按年龄四分位数分层.
研究的目的:
- 研究年龄如何影响传染性内心炎的流行病学,临床,微生物学和预后方面.
- 分析左侧感染性内心炎特征的与年龄相关的变化.
主要方法:
- 在3个三级中心对600个左侧感染性内心炎发作进行了回顾性分析.
- 患者的分层分为年龄四分之一.
- 107个年龄组之间的变量进行比较.
主要成果:
- 年龄较大的患者有更高的女性性,先前存在的心脏病,糖尿病,癌症和Enterococci和Streptococcus bovis感染率.
- 年轻的患者更频繁地出现了膜衰竭,穿孔和金黄色葡萄球菌感染.
- 治疗方法各不相同,老年患者更可能只接受医疗管理,导致结果更差,手术死亡率增加.
结论:
- 左侧传染性内心炎的年龄增加与减少膜功能障碍和更有利的微生物特征有关.
- 然而,晚年与这些患者的外科死亡率显著增加有关.
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