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Updated: Jun 16, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
07:59

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

Published on: October 4, 2019

双重乳标记的帕丘利酒精来自单一标记的[2-(2) H(1)]法纳西二酸盐的循环,由重组帕丘洛尔合成酶催化

Juan A Faraldos1, Shuiqin Wu, Joe Chappell

  • 1Department of Chemistry, University of Illinois, 600 South Mathews Avenue, Urbana, Illinois 61801, USA.

Journal of the American Chemical Society
|February 13, 2010
PubMed
概括

这项研究揭示了如何使用带标记的法二酸盐 (farnesyl diphosphate) 制造帕丘醇合成酶 (PTS). 这项研究澄清了酶的机制,确定了1,3-化物转移和一种新的中间体.

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