相关实验视频

Updated: Jun 16, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

使用立体选择性迪尔斯-阿尔德循环添加来检测烯-烯相互作用中的替代物效应

Steven E Wheeler1, Anne J McNeil, Peter Müller

  • 1Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, USA.

Journal of the American Chemical Society
|February 18, 2010
PubMed
概括

使用迪尔斯-阿尔德反应,探索了-三明治复合物的替代效应. 结果显示,pi-stacking相互作用,而不是pi-system捐赠,驱动这些效应,挑战现有模型.

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The Diels–Alder reaction is an example of a thermal pericyclic reaction between a conjugated diene and an alkene or alkyne, commonly referred to as a dienophile. The reaction involves a concerted movement of six π electrons, four from the diene and two from the dienophile, forming an unsaturated six-membered ring. As a result, these reactions are classified as [4+2] cycloadditions.
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