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在人类癌症中体质副本数量改变的景观

Rameen Beroukhim1, Craig H Mermel, Dale Porter

  • 1Cancer Program and Medical and Population Genetics Group, The Broad Institute of M.I.T. and Harvard, 7 Cambridge Center.

Nature
|February 19, 2010
PubMed
概括

在人类癌症中识别频繁的基因组变化揭示了关键的瘤发生基因. 在多种癌症类型中发现了许多新的癌症驱动基因,突出显示了共同的遗传脆弱性.

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