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Updated: Jun 16, 2026

Functional Characterization of RING-Type E3 Ubiquitin Ligases In Vitro and In Planta
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活动部位的改造伴随着SUMO E1 E1中酸键的形成

Shaun K Olsen1, Allan D Capili, Xuequan Lu

  • 1Structural Biology, Sloan-Kettering Institute, New York, New York 10065, USA.

Nature
|February 19, 2010
PubMed
概括

这项研究揭示了SUMO蛋白的E1酶激活背后的结构机制. 晶体结构显示了E1酶如何重塑其催化域以形成关键的硫键.

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