假药效应的生物学,临床和伦理方面的进展
Damien G Finniss1, Ted J Kaptchuk, Franklin Miller
1University of Sydney Pain Management and Research Institute, Royal North Shore Hospital, St Leonards, NSW, Australia. dfinniss@med.usyd.edu.au
Lancet (London, England)
|February 23, 2010
概括
安慰剂效应是真正的精神生物学反应,而不仅仅是惰性物质. 研究表明,这些效应在临床和实验室环境中是强大的,即使没有安慰剂.
科学领域:
- 心理神经免疫学 心理神经免疫学
- 临床心理学 临床心理学
- 医学伦理 医学伦理
背景情况:
- 传统上,安慰剂被视为在临床试验中用于控制的惰性物质.
- 最近的研究将安慰剂效应重新定义为真正的精神生物学现象.
- 这些效应受到更广泛的治疗背景的影响.
研究的目的:
- 为了强调安慰剂效应是真正的精神生物学事件.
- 为了强调安慰剂效应在不同环境中的强度.
- 探索将安慰剂机制纳入常规临床护理中的潜力.
主要方法:
- 关于安慰剂效应的最新科学文献的综述.
- 对安慰剂反应背后的精神生物学机制的分析.
- 在实验和临床环境中检查安慰剂效应的证据.
主要成果:
- 据证明,安慰剂效应是真正的精神生物学事件.
- 这些效应在实验室和临床环境中都是强大而可观测的.
- 有证据表明,即使不使用安慰剂,安慰剂效应也可能发生.
结论:
- 安慰剂效应是治疗背景的组成部分.
- 进一步的研究可以促进安慰剂机制在医疗保健中的伦理应用.
- 促进研究整合可以鼓励利用这些固有的效应的治疗方法.
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