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Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
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在无极环境中通过低温NMR光谱学研究的非离子二核酸类型的基底识别

Zhou Xiao1, Klaus Weisz

  • 1Institute of Biochemistry, Ernst-Moritz-Arndt University Greifswald, Felix-Hausdorff-Str. 4, D-17489 Greifswald, Germany.

Journal of the American Chemical Society
|February 26, 2010
PubMed
概括

修改后的二核酸类似物A(Si) T和T(Si) A在非水性环境中进行了研究. A(Si) T形成了一个稳定的双重复合体,而T(Si) A表现出结构上的灵活性和较弱的基因配对,影响了DNA间接器结合.

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