视网膜母细胞瘤蛋白的G1/S酸化与对核区的异化亲和关系有关

S Mittnacht1, R A Weinberg

  • 1Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge 02142.

Cell
|May 3, 1991
PubMed
概括

视网膜母细胞瘤蛋白 (pRB) 在非化时紧密结合于细胞核,这种状态对于增长抑制至关重要. 过酸化释放pRB,与细胞周期进展相吻合,并可能使病毒上蛋白干扰.

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