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SIRT3通过可逆酶脱乙化来调节线粒体脂肪酸的氧化

Matthew D Hirschey1, Tadahiro Shimazu, Eric Goetzman

  • 1Gladstone Institute of Virology and Immunology, San Francisco, California 94158, USA.

Nature
|March 6, 2010
PubMed
概括

缺乏Sirtuin 3 (SIRT3) 的小鼠在禁食期间表现出脂肪酸氧化受损,这是由于LCAD等关键酶的过化,导致代谢功能障碍. 这突出了SIRT3的功能.

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