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Updated: Jun 15, 2026

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通过对活细胞的可逆二元化来控制EGF受体激活的空间控制

Inhee Chung1, Robert Akita, Richard Vandlen

  • 1Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.

Nature
|March 9, 2010
PubMed
概括

皮表皮生长因子受体 (EGFR) 单体在带结合之前自发形成二次体,这对于信号传输至关重要. 这些EGFR二聚体在细胞外围被丰富,增强生长因子反应.

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