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Updated: May 5, 2026

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
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Published on: September 20, 2019

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提前停止随机试验以获益并估计治疗效果:系统性审查和元回归分析

Dirk Bassler1, Matthias Briel, Victor M Montori

  • 1Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.

JAMA
|March 25, 2010
PubMed
概括

随机对照试验 (RCT) 为了获益而提前停止,高估治疗效果. 无论停止规则如何,这种偏见仍然存在,并且在较小的研究中更明显,事件较少.

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