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Chromatin Immunoprecipitation from Human Embryonic Stem Cells
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胚胎多能性的染色体特征是在基因组激活过程中建立的

Nadine L Vastenhouw1, Yong Zhang, Ian G Woods

  • 1Department of Molecular and Cellular Biology, Harvard University, 16 Divinity Avenue, Cambridge, Massachusetts 02138, USA.

Nature
|March 26, 2010
PubMed
概括

在母细胞转变过程中,关键的组素修饰,如H3K4me3和H3K27me3,建立了双价和单价染色体域,为胚胎基因的激活和多能性做好了准备.

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