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Detection of Homologous Recombination Intermediates via Proximity Ligation and Quantitative PCR in Saccharomyces cerevisiae
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双霍利德结是DNA断裂修复过程中的中间体

Malgorzata Bzymek1, Nathaniel H Thayer, Steve D Oh

  • 1Department of Microbiology, University of California Davis, Davis, California 95616, USA.

Nature
|March 30, 2010
PubMed
概括

这项研究确定了双霍莱德结 (DHJs) 作为DNA双链断裂 (DSB) 修复的关键中间体,在线粒分裂和半分裂期间. 然而,在这两种细胞分裂过程中,它们的形成受到不同的调节.

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