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Updated: Jun 14, 2026

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Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
Published on: January 25, 2016
突然的感官神经神经听力损失
Benjamin E Schreiber1, Charlotte Agrup, Dorian O Haskard
1Royal Free Hampstead NHS Trust, London, UK.
Lancet (London, England)
|April 6, 2010
概括
突然感觉神经听力损失 (SSNHL) 往往是特异性的,但需要紧急评估. 虽然恢复是常见的,但尽管尚未证明有效性,但仍建议使用高剂量的皮质类固醇,这需要进一步的临床试验.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 神经学 神经学
- 内部医学 内部医学
背景情况:
- 突然感觉神经听力损失 (SSNHL) 通常是单边的,可能伴有耳和头.
- SSNHL的病因在很大程度上仍未确定,包括感染,血管问题和免疫系统功能障碍在内的原因被提议.
- 紧急医疗评估至关重要,以排除诸如血管事件或恶性瘤等严重疾病.
研究的目的:
- 审查当前对突然感官神经神经听力损失的理解.
- 讨论SSNHL的诊断考虑和管理策略.
- 突出进一步研究和临床试验的需要.
主要方法:
- 关于突然感觉神经神经听力损失的现有文献的审查.
- 怀疑SSNHL的临床检查协议.
- 分析常用的治疗方式.
主要成果:
- 大约50%的患者在两周内自发恢复.
- 使用各种治疗方法,包括皮质类固醇,抗病毒药物和氧气疗法.
- 没有任何单一的治疗方法证明了最终的疗效.
结论:
- 建议使用高剂量的口服皮质类固醇在短时间内,尽管缺乏经过证明的有效性.
- 进一步研究SSNHL的病原体是必不可少的.
- 基于证据的管理准则要求开发更强大的临床试验.
相关概念视频
Hearing
When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.
Unrenewable Cells
In humans, the photoreceptor cells of the eye and sensory hair cells of the ear lack stem cells. These cells are thus unrenewable and cannot be replaced when they are damaged or destroyed.
Photoreceptors
The retina is composed of several layers and contains specialized cells called photoreceptors. The photoreceptors (rods and cones) change their membrane potential when stimulated by light energy. There are two types of photoreceptors—rods and cones—which differ in the shape of their outer...
Photoreceptors
The retina is composed of several layers and contains specialized cells called photoreceptors. The photoreceptors (rods and cones) change their membrane potential when stimulated by light energy. There are two types of photoreceptors—rods and cones—which differ in the shape of their outer...
Sensation
Sensory receptors are specialized neurons that respond to specific types of external stimuli, initiating the process known as sensation. This occurs when sensory input, such as light entering the eye, is detected by these receptors, causing chemical changes in the cells of the retina. These cells then convert the sensory stimulus into action potentials that are transmitted to the central nervous system, a process termed transduction.
Absolute thresholds can quantify the sensitivity of sensory...
Absolute thresholds can quantify the sensitivity of sensory...
Auditory Pathway
Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking the...
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking the...
Hair Cells
Hair cells are the sensory receptors of the auditory system—they transduce mechanical sound waves into electrical energy that the nervous system can understand. Hair cells are located in the organ of Corti within the cochlea of the inner ear, between the basilar and tectorial membranes. The actual sensory receptors are called inner hair cells. The outer hair cells serve other functions, such as sound amplification in the cochlea, and are not discussed in detail here.
Perceiving Loudness, Pitch, and Location
The human brain perceives pitch through two primary mechanisms reflected in place theory and frequency theory. Each mechanism describes how sound waves are interpreted as specific pitches by the brain, offering insights into the intricate processes of auditory perception.
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by identifying...
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by identifying...

