在不对称的催化-动态减小运动分辨率进入 (S-profens) 中使用来自archael超热的强大的脱酶

Jacob A Friest1, Yukari Maezato, Sylvain Broussy

  • 1Department of Chemistry, University of Nebraska, Lincoln, Nebraska 68588, USA.

概括

这项研究引入了来自Sulfolobus solfataricus的高效酒精脱酶 (SsADH-10),用于不对称的合成. 该酶使烯型化物具有高度选择性的动态还原动力学分辨率 (DYRKR),显示出广泛的基质耐受性和可回收性.

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