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早期识别和预防慢性病
Matthew T James1, Brenda R Hemmelgarn, Marcello Tonelli
1Department of Medicine, University of Calgary, Calgary, AB, Canada.
Lancet (London, England)
|April 13, 2010
概括
早期诊断和干预是管理慢性病 (CKD) 和降低风险的关键. 有效的策略,包括血压控制和首选药物,可以减缓CKD的进展和心血管风险.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 心血管医学 心血管医学
- 公共卫生 公共卫生
背景情况:
- 慢性病 (CKD) 是一个日益严重的全球健康问题.
- 通过蛋白尿或降低估计球过率 (eGFR) 的早期检测对于干预至关重要.
- 查在发达国家的高风险人群中最有效.
研究的目的:
- 审查目前用于早期诊断和治疗CKD的策略.
- 突出有效的治疗方法来减缓CKD进展和降低心血管风险.
- 确定改善风险分层和管理模式的需求.
主要方法:
- 关于CKD诊断和管理的当前指导方针和研究的文献综述.
- 对血压控制,蛋白尿和降低心血管风险的有效干预措施的分析.
- 讨论查策略和未来的研究需求.
主要成果:
- 通过蛋白尿或降低的EGFR早期诊断可以及时进行干预.
- 治疗高血压,使用ACE抑制剂/ARB和血糖控制至关重要.
- 类药物和阿司匹林有利于高风险的CKD患者;需要新的方法来预测进展.
结论:
- 慢性瘤的管理需要一个多方面的方法,包括早期检测和风险因素控制.
- 有针对性的查和优化的治疗策略可以改善结果.
- 需要进一步的研究,以更好地预测CKD进展和心血管事件.
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