单胞胎双胞胎的基因组,表观基因组和RNA序列对多发性硬化症不一致

Sergio E Baranzini1, Joann Mudge, Jennifer C van Velkinburgh

  • 1Department of Neurology, University of California at San Francisco, San Francisco, California 94143, USA. sebaran@cgl.ucsf.edu

Nature
|April 30, 2010
PubMed
概括

患有多发性硬化症 (MS) 的同卵双胞胎没有显著的遗传或表观遗传差异,挑战了环境因素单独导致疾病不一致的想法. 这项研究对双胞胎基因组和表观基因组进行了测序,以了解MS患者的自然与培养对比.

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