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一个单一的沃森-克里克G x C基对在水中:疏水性空洞中的水性键

Tomohisa Sawada1, Makoto Fujita

  • 1Department of Applied Chemistry, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.

Journal of the American Chemical Society
|May 1, 2010
PubMed
概括

研究人员创建了一个合成腔体,以使水中的关氨酸-氨酸 (G x C) 基配对. 这种人造的疏水口袋屏蔽了结位,促进了稳定的核酸相互作用和选择性的G x C配对.

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